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Article

The relationship between body mass index and the risk of development of Dupuytren's disease: a Mendelian randomization study.

The Journal of hand surgery, European volume - 1 May 2021

Majeed Mustafa, Wiberg Akira, Ng Michael, Holmes Michael V, Furniss Dominic

Abstract excerpt

We performed Mendelian randomization analyses of body mass index and waist-hip ratio adjusted for body mass index in Dupuytren's disease using summary statistics from genome-wide association study meta-analyses. We found that adiposity is causally protective against Dupuytren's disease, with the inverse-variance weighted Mendelian randomization analysis estimating that a 1 standard deviation increase in body mass...

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PMID: 32972297
DOI: 10.1177/1753193420958553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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