Article
Upper Gastrointestinal Cancer Risk and Surveillance Outcomes in Li-Fraumeni Syndrome.
The American journal of gastroenterology - 1 Dec 2020
Katona Bryson W, Powers Jacquelyn, McKenna Danielle B, Long Jessica M, Le Anh N, Hausler Ryan, Zelley Kristin, Jennings Sarah, Domchek Susan M, Nathanson Katherine L, MacFarland Suzanne P, Maxwell Kara N
Abstract excerpt
INTRODUCTION: To assess the upper gastrointestinal (UGI) cancer risk and surveillance outcomes in Li-Fraumeni syndrome (LFS). METHODS: Analysis of the International Agency for Research on Cancer database and a single-center adult LFS cohort. RESULTS: UGI cancer was present in 7.2% of families and 3.9% of individuals with a pathogenic/likely pathogenic TP53 mutation in International Agency for Research on Cancer;...
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