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Article

IFI30 expression is an independent unfavourable prognostic factor in glioma.

Journal of cellular and molecular medicine - 1 Nov 2020

Liu Xiu, Song Chunyan, Yang Shoubo, Ji Qiang, Chen Feng, Li Wenbin

Abstract excerpt

Gamma-interferon-inducible lysosomal thiol reductase, the only known lysosomal thiol reductase, is encoded by gene IFI30 and expressed constitutively in antigen-presenting cells. Our comprehensive study on IFI30 in gliomas found its expression to be high in glioblastomas and in gliomas with a mesenchymal subtype or wild-type isocitrate dehydrogenase, all of which indicated the malignancy and poor outcomes of...

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Identifiers

PMID: 32969157
DOI: 10.1111/jcmm.15758
PMCID: PMC7686962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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