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Article

Conserved Tryptophan Motifs in the Large Tegument Protein pUL36 Are Required for Efficient Secondary Envelopment of Herpes Simplex Virus Capsids.

Journal of virology - 1 Jun 2016

Ivanova Lyudmila, Buch Anna, Döhner Katinka, Pohlmann Anja, Binz Anne, Prank Ute, Sandbaumhüter Malte, Bauerfeind Rudolf, Sodeik Beate

Abstract excerpt

UNLABELLED: Herpes simplex virus (HSV) replicates in the skin and mucous membranes, and initiates lytic or latent infections in sensory neurons. Assembly of progeny virions depends on the essential large tegument protein pUL36 of 3,164 amino acid residues that links the capsids to the tegument proteins pUL37 and VP16. Of the 32 tryptophans of HSV-1-pUL36, the tryptophan-acidic motifs (1766)WD(1767) and...

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Identifiers

PMID: 27009950
DOI: 10.1128/JVI.03167-15
PMCID: PMC4934747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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