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Article

Obesity-Related Traits and the Development of Rheumatoid Arthritis: Evidence From Genetic Data.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Feb 2021

Tang Bowen, Shi Huwenbo, Alfredsson Lars, Klareskog Lars, Padyukov Leonid, Jiang Xia

Abstract excerpt

OBJECTIVE: To investigate the association between obesity-related traits and risk of rheumatoid arthritis (RA). METHODS: We conducted genetic correlation analysis and a 2-sample Mendelian randomization (MR) study, using genome-wide genetic data based on >850,000 individuals of European ancestry. Summary statistics were collected from the largest genome-wide association study conducted to date for body mass index...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32964675
DOI: 10.1002/art.41517
PMCID: PMC7898325

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