Article
The Causal Effect of Obesity on the Risk of 15 Autoimmune Diseases: A Mendelian Randomization Study.
Obesity facts - 1 Jan 2023
Li Xunliang, Zhu Jie, Zhao Wenman, Zhu Yuyu, Zhu Li, Shi Rui, Wang Zhijuan, Pan Haifeng, Wang Deguang
Abstract excerpt
INTRODUCTION: Observational studies have shown that obesity is a risk factor for various autoimmune diseases. However, the causal relationship between obesity and autoimmune diseases is unclear. Mendelian randomization (MR) was used to investigate the causal effects of obesity on 15 autoimmune diseases. METHODS: MR analysis employed instrumental variables, specifically single-nucleotide polymorphisms associated...
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