Article
Association between endometriosis and arthritis: results from NHANES 1999-2006, genetic correlation analysis, and Mendelian randomization study.
Frontiers in immunology - 1 Jan 2024
Xu Huanying, Zou Haoxi, Wen Qidan, Xing Xiaoyan, Xu Ningning, Wu Suzhen
Abstract excerpt
Background: Previous studies reported that endometriosis may have a higher risk of arthritis. However, it remains unclear whether the association between endometriosis and arthritis has genetic correlations, or the relationship is causal. Linkage Disequilibrium Score (LDSC) and Mendelian Randomization (MR) analyses use genetic variation as a natural experiment to explore genetic correlations and causal inferences...
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