Article
Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury.
Molecular neurobiology - 1 Jan 2021
Kim Juri, Joshi Hari Prasad, Sheen Seung Hun, Kim Kyoung-Tae, Kyung Jae Won, Choi Hyemin, Kim Ye Won, Kwon Su Yeon, Roh Eun Ji, Choi Un Yong, Sohn Seil, Kim Yong Ho, Park Chul-Kyu, Kumar Hemant, Han In-Bo
Abstract excerpt
Resolvins, a new family from the endogenous specialized pro-resolving mediators (SPMs), promote the resolution of the inflammatory response. Resolvin D3 (RvD3), a docosahexaenoic acid (DHA) product, has been known to suppress the inflammatory response. However, the anti-inflammatory and neuroprotective effects of RvD3 are not known in a model of spinal cord injury (SCI). Here, we investigated the...
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