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Article

Resolvin D1 attenuates the inflammatory process in mouse model of LPS-induced keratitis.

Journal of cellular and molecular medicine - 1 Nov 2020

Petrillo Francesco, Trotta Maria Consiglia, Bucolo Claudio, Hermenean Anca, Petrillo Arianna, Maisto Rosa, Pieretti Gorizio, Pietropaolo Michela, Ferraraccio Franca, Gagliano Caterina, Galdiero Marilena, D'Amico Michele

Abstract excerpt

The aim of this study was to investigate the effects of the lipid mediator Resolvin D1 in experimental keratitis. C57BL/6J mice were injected with lipopolysaccharide (2 µg/eye), and after 24 hours, the corneal damage was assessed. Clinical score was quantified, and corneal inflammatory biomarkers were detected by immunohistochemistry. A robust accumulation of sub-epithelial macrophages and polymorphonuclear...

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Identifiers

PMID: 33058526
DOI: 10.1111/jcmm.15633
PMCID: PMC7686975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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