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Article

Whole genome sequencing analysis for cancer genomics and precision medicine.

Cancer science - 1 Mar 2018

Nakagawa Hidewaki, Fujita Masashi

Abstract excerpt

Explosive advances in next-generation sequencer (NGS) and computational analyses have enabled exploration of somatic protein-altered mutations in most cancer types, with coding mutation data intensively accumulated. However, there is limited information on somatic mutations in non-coding regions, including introns, regulatory elements and non-coding RNA. Structural variants and pathogen in cancer genomes remain...

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Identifiers

PMID: 29345757
DOI: 10.1111/cas.13505
PMCID: PMC5834793

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