Article
Facility-dependent metabolic phenotype and gut bacterial composition in CD-1 mice from a single vendor: A brief report.
PloS one - 1 Jan 2020
Unger Allison L, Eckstrom Korin, Jetton Thomas L, Kraft Jana
Abstract excerpt
Utilization of murine models remains a valuable tool in biomedical research, yet, disease phenotype of mice across studies can vary considerably. With advances in next generation sequencing, it is increasingly recognized that inconsistencies in host phenotype can be attributed, at least in part, to differences in gut bacterial composition. Research with inbred murine strains demonstrates that housing conditions...
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