Article
Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice.
Scientific reports - 25 Jun 2014
Rogers G B, Kozlowska J, Keeble J, Metcalfe K, Fao M, Dowd S E, Mason A J, McGuckin M A, Bruce K D
Abstract excerpt
Despite the fundamental contribution of the gut microbiota to host physiology, the extent of its variation in genetically-identical animals used in research is not known. We report significant divergence in both the composition and metabolism of gut microbiota in genetically-identical adult C57BL/6 mice housed in separate controlled units within a single commercial production facility. The reported divergence in...
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