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Article

IL17RA in early-onset coronary artery disease: Total leukocyte transcript analysis and promoter polymorphism (rs4819554) association.

Cytokine - 1 Dec 2020

Coto Eliecer, Pascual Isaac, Avanzas Pablo, Cuesta-Lavona Elías, Lorca Rebeca, Martín María, Vázquez-Coto Daniel, Díaz-Corte Carmen, Morís César, Rodríguez-Reguero Julián, Gómez Juan

Abstract excerpt

BACKGROUND AND AIMS: The interleukin-17 (IL-17) pathway would play an important role in the pathogenesis of atherosclerosis and coronary-artery disease (CAD). The IL-17 inflammatory mediators are expressed by Th17 cells, a group of CD4 + leukocytes that infiltrate the vascular milieu and are pivotal in the origin, progression, stability and rupture of the atherosclerotic lesion. Cigarette smoke compounds...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32950026
DOI: 10.1016/j.cyto.2020.155285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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