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Article

Genetic variation associated with childhood and adult stature and risk of MYCN-amplified neuroblastoma.

Cancer medicine - 1 Nov 2020

Semmes Eleanor C, Shen Erica, Cohen Jennifer L, Zhang Chenan, Wei Qingyi, Hurst Jillian H, Walsh Kyle M

Abstract excerpt

BACKGROUND: Neuroblastoma is the most common pediatric solid tumor. MYCN-amplification is an important negative prognostic indicator and inherited genetic contributions to risk are incompletely understood. Genetic determinants of stature increase risk of several adult and childhood cancers, but have not been studied in neuroblastoma despite elevated neuroblastoma incidence in children with congenital overgrowth...

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Identifiers

PMID: 32945147
DOI: 10.1002/cam4.3458
PMCID: PMC7643638

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