Article
Genetic polymorphisms of IL-17A, IL-17F, TLR4 and miR-146a in association with the risk of pulmonary tuberculosis.
Scientific reports - 24 Jun 2016
Wang Min, Xu Guisheng, Lü Lingshuang, Xu Kun, Chen Yongzhong, Pan Hongqiu, Burstrom Bo, Burstrom Kristina, Wang Jianming
Abstract excerpt
Genetic factors affect host susceptibility to pathogens. In this population-based case control study, we explored the genetic polymorphisms of IL-17, TLR4 and miR-146a in association with pulmonary tuberculosis in a Chinese Han population. We recruited 1601 pulmonary tuberculosis patients matched with 1526 healthy controls and genotyped twelve functional single nucleotide polymorphisms (SNPs). After the...
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