Article
Role of telomeres and associated maintenance genes in Type 2 Diabetes Mellitus: A review.
Diabetes research and clinical practice - 1 Dec 2016
Sethi Itty, Bhat G R, Singh Vinod, Kumar Rakesh, Bhanwer A J S, Bamezai Rameshwar N K, Sharma Swarkar, Rai Ekta
Abstract excerpt
Type 2 Diabetes Mellitus (T2DM), a multifactorial complex disorder, is emerging as a major cause of morbidity, mortality and socio-economic burden across the world. Despite huge efforts in understanding genetics of T2DM, only ∼10% of the genetic factors have been identified so far. Telomere attrition, a natural phenomenon has recently emerged in understanding the pathophysiology of T2DM. It has been indicated...
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