Article
Genomic risk variants at 1p13.3, 1q41, and 3q22.3 are associated with subsequent cardiovascular outcomes in healthy controls and in established coronary artery disease.
Circulation. Cardiovascular genetics - 1 Dec 2011
Ellis Katrina L, Frampton Chris M, Pilbrow Anna P, Troughton Richard W, Doughty Rob N, Whalley Gillian A, Ellis Chris J, Skelton Lorraine, Thomson Judith, Yandle Tim G, Richards A Mark, Cameron Vicky A
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified gene variants associated with coronary artery disease risk; however, whether they affect disease progression is largely unknown. This study investigated associations between polymorphisms at 1p13.3 (rs599839), 1q41 (rs17465637), and 3q22.3 (rs9818870) and cardiovascular outcomes in healthy volunteers and in patients with established heart disease....
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