Using the "Hidden" genome to improve classification of cancer types.

Abstract excerpt

It is increasingly common clinically for cancer specimens to be examined using techniques that identify somatic mutations. In principle, these mutational profiles can be used to diagnose the tissue of origin, a critical task for the 3% to 5% of tumors that have an unknown primary site. Diagnosis of primary site is also critical for screening tests that employ circulating DNA. However, most mutations observed in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Exome Sequencing
• Share to Likelihood Functions
• Share to Mutation