Article
Utilizing somatic mutation data from numerous studies for cancer research: proof of concept and applications.
Oncogene - 15 Jun 2017
Amar D, Izraeli S, Shamir R
Abstract excerpt
Large cancer projects measure somatic mutations in thousands of samples, gradually assembling a catalog of recurring mutations in cancer. Many methods analyze these data jointly with auxiliary information with the aim of identifying subtype-specific results. Here, we show that somatic gene mutations alone can reliably and specifically predict cancer subtypes. Interpretation of the classifiers provides useful...
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