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Article

Retained primary teeth in STAT3 hyper-IgE syndrome: early intervention in childhood is essential.

Orphanet journal of rare diseases - 10 Sept 2020

Meixner Iris, Hagl Beate, Kröner Carolin I, Spielberger Benedikt D, Paschos Ekaterini, Dückers Gregor, Niehues Tim, Hesse Ronny, Renner Ellen D

Abstract excerpt

BACKGROUND: STAT3 hyper-IgE syndrome (STAT3-HIES) is a rare primary immunodeficiency that clinically overlaps with atopic dermatitis. In addition to eczema, elevated serum-IgE, and recurrent infections, STAT3-HIES patients suffer from characteristic facies, midline defects, and retained primary teeth. To optimize dental management we assessed the development of dentition and the long-term outcomes of dental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32912316
DOI: 10.1186/s13023-020-01516-3
PMCID: PMC7488068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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