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Article

Paracrine signaling of human mesenchymal stem cell modulates retinal microglia population number and phenotype in vitro.

Experimental eye research - 1 Nov 2020

Teixeira-Pinheiro Leandro C, Toledo Maria F, Nascimento-Dos-Santos Gabriel, Mendez-Otero Rosalia, Mesentier-Louro Louise A, Santiago Marcelo F

Abstract excerpt

PURPOSE: Cellular therapy with mesenchymal stem cells (MSC) is emerging as an effective option to treat optic neuropathies. In models of retinal degeneration, MSC injected in the vitreous body protects injured retinal ganglion cells and stimulate their regeneration, however the mechanism is still unknown. Considering the immunomodulating proprieties of MSC and the controversial role of microglial contribution on...

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Identifiers

PMID: 32910940
DOI: 10.1016/j.exer.2020.108212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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