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Article

Persistent recovery of pancreatic function in patients with cystic fibrosis after ivacaftor.

Pediatric pulmonology - 1 Dec 2020

Munce Danielle, Lim Meerana, Akong Kathryn

Abstract excerpt

Exocrine pancreatic insufficiency (EPI), which leads to malabsorption and poor weight gain, is seen in 85% of patients with cystic fibrosis (CF). EPI is treated with pancreatic enzyme replacement therapy taken with each meal. The highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulator, ivacaftor, restores CFTR function in patients with responsive mutations. It is a widely held view...

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Identifiers

PMID: 32910556
DOI: 10.1002/ppul.25065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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