Article
Early decline of pancreatic function in cystic fibrosis patients with class 1 or 2 CFTR mutations.
Journal of pediatric gastroenterology and nutrition - 1 Feb 2005
Walkowiak Jaroslaw, Sands Dorota, Nowakowska Anna, Piotrowski Robert, Zybert Katarzyna, Herzig Karl-Heinz, Milanowski Andrzej
Abstract excerpt
BACKGROUND: Most cystic fibrosis (CF) patients develop steatorrhea and require pancreatic enzyme replacement therapy. However, there are few data regarding the decline of exocrine pancreatic function within the first years of life in relation to CF genotype. We assessed the decline of pancreatic function in CF infants carrying class 1 or 2 CFTR mutations who were diagnosed in a neonatal screening program....
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