Article
Rapid Detection of Azole-Resistant Aspergillus fumigatus in Clinical and Environmental Isolates by Use of a Lab-on-a-Chip Diagnostic System.
Journal of clinical microbiology - 21 Oct 2020
Yu Ling-Shan, Rodriguez-Manzano Jesus, Moser Nicolas, Moniri Ahmad, Malpartida-Cardenas Kenny, Miscourides Nicholas, Sewell Thomas, Kochina Tatiana, Brackin Amelie, Rhodes Johanna, Holmes Alison H, Fisher Matthew C, Georgiou Pantelis
Abstract excerpt
Aspergillus fumigatus has widely evolved resistance to the most commonly used class of antifungal chemicals, the azoles. Current methods for identifying azole resistance are time-consuming and depend on specialized laboratories. There is an urgent need for rapid detection of these emerging pathogens at point-of-care to provide the appropriate treatment in the clinic and to improve management of environmental...
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