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Article

Hair dysmorphology in the R6/1 and R6/2 mouse models of Huntington's disease.

Gene - 10 Jan 2021

Pierzynowska Karolina, Podlacha Magdalena, Łuszczek Dorota, Rintz Estera, Gaffke Lidia, Szczudło Zuzanna, Tomczyk Marta, Smoleński Ryszard T, Węgrzyn Grzegorz

Abstract excerpt

Huntington's disease (HD), caused by expansion of CAG repeats in the 1st exon of the HTT gene, is a disorder inherited in an autosomal dominant manner. HD symptoms include chorea, behavioral disturbances and cognitive decline. Although it is described as a neurodegenerative disease, due to expression of HTT in all types of cells, peripheral symptoms also occur. R6/1 and R6/2 mouse lines, which demonstrate many...

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PMID: 32898606
DOI: 10.1016/j.gene.2020.145133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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