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Article

Abnormal morphology of peripheral cell tissues from patients with Huntington disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2010

Squitieri Ferdinando, Falleni Alessandra, Cannella Milena, Orobello Sara, Fulceri Federica, Lenzi Paola, Fornai Francesco

Abstract excerpt

We investigated the genotype-dependency of morphological abnormalities in peripheral cells from Huntington disease (HD) patients. Cell cultures derived from skin and muscle biopsies showed a different set of abnormalities depending on the genotype (i.e. heterozygous and homozygous for CAG mutations) and the tissue (i.e. fibroblasts and myoblasts). In general, homozygotes' cell lines showed massive ultrastructural...

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PMID: 19834779
DOI: 10.1007/s00702-009-0328-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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