Article
SARS-CoV-2 envelope protein topology in eukaryotic membranes.
Open biology - 1 Sept 2020
Duart Gerard, García-Murria Mª Jesús, Grau Brayan, Acosta-Cáceres José M, Martínez-Gil Luis, Mingarro Ismael
Abstract excerpt
Coronavirus E protein is a small membrane protein found in the virus envelope. Different coronavirus E proteins share striking biochemical and functional similarities, but sequence conservation is limited. In this report, we studied the E protein topology from the new SARS-CoV-2 virus both in microsomal membranes and in mammalian cells. Experimental data reveal that E protein is a single-spanning membrane protein...
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