Article
Genetic mutations associated with susceptibility to perioperative complications in a longitudinal biorepository with integrated genomic and electronic health records.
British journal of anaesthesia - 1 Dec 2020
Douville Nicholas J, Kheterpal Sachin, Engoren Milo, Mathis Michael, Mashour George A, Hornsby Whitney E, Willer Cristen J, Douville Christopher B
Abstract excerpt
BACKGROUND: Existing genetic information can be leveraged to identify patients with susceptibilities to conditions that might impact their perioperative care, but clinicians generally have limited exposure and are not trained to contextualise this information. We identified patients with genetic susceptibilities to anaesthetic complications using a perioperative biorepository and characterised the concordance...
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