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Article

Update on the Role of NFκB in Promoting Aggressive Phenotypes of Estrogen Receptor-Positive Breast Cancer.

Endocrinology - 1 Oct 2020

Smart Emily, Semina Svetlana E, Frasor Jonna

Abstract excerpt

The majority of breast cancers are diagnosed as estrogen receptor-positive (ER+) and respond well to ER-targeted endocrine therapy. Despite the initial treatability of ER+ breast cancer, this subtype still accounts for the majority of deaths. This is partly due to the changing molecular characteristics of tumors as they progress to aggressive, metastatic, and frequently therapy resistant disease. In these...

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Share to Breast Neoplasms
Share to Disease Progression
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Neoplasm Invasiveness

Share to NF-kappa B

Share to Receptors, Estrogen

Share to Signal Transduction

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Identifiers

PMID: 32887995
DOI: 10.1210/endocr/bqaa152
PMCID: PMC7521126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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