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Article

Family history and the natural history of colorectal cancer: systematic review.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2015

Henrikson Nora B, Webber Elizabeth M, Goddard Katrina A, Scrol Aaron, Piper Margaret, Williams Marc S, Zallen Doris T, Calonge Ned, Ganiats Theodore G, Janssens A Cecile J W, Zauber Ann, Lansdorp-Vogelaar Iris, van Ballegooijen Marjolein, Whitlock Evelyn P

Abstract excerpt

PURPOSE: Family history of colorectal cancer (CRC) is a known risk factor for CRC and encompasses both genetic and shared environmental risks. METHODS: We conducted a systematic review to estimate the impact of family history on the natural history of CRC and adherence to screening. RESULTS: We found high heterogeneity in family-history definitions, the most common definition being one or more first-degree...

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Identifiers

PMID: 25590981
DOI: 10.1038/gim.2014.188
PMCID: PMC4955831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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