Article
[Constructing iPS cell-based platforms for disease modeling and drug discovery in cardiovascular fields: Phenotype analysis using self-organization and new imaging techniques].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica - 1 Jan 2020
Lee Jong-Kook
Abstract excerpt
Disease-specific iPS cells have been considered and used as platforms for disease modeling and drug discovery for intractable diseases. In the field of cardiovascular medicine, iPS cells have been generated from patients with heart diseases including inherited cardiomyopathy. The disease-specific iPS cells showed the certain parts of phenotype of the disease on culture dishes in in vitro systems, but the cells do...
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