Article
PPARγ enhanced Adiponectin polymerization and trafficking by promoting RUVBL2 expression during adipogenic differentiation.
Gene - 5 Jan 2021
Zhu Daiyun, Xu Le, Wei Xuan, Xia Benzeng, Gong Yuqing, Li Qinjin, Chen Xiaodong
Abstract excerpt
Adipocyte differentiation is an essential part of adipose tissue development, and is closely related to obesity and obesity-related diseases. In this study, we found that the expression of PPARγ, RUVBL2 and Adiponectin were concurrently obviously increased in the 5th-7th day of 3T3-L1 cell differentiation. PPARγ overexpression or the PPARγ activator facilitated Adiponectin trafficking and secretion and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
