Article
HNF1B, EZH2 and ECI2 in prostate carcinoma. Molecular, immunohistochemical and clinico-pathological study.
Scientific reports - 1 Sept 2020
Dundr Pavel, Bártů Michaela, Hojný Jan, Michálková Romana, Hájková Nikola, Stružinská Ivana, Krkavcová Eva, Hadravský Ladislav, Kleissnerová Lenka, Kopejsková Jana, Hiep Bui Quang, Němejcová Kristýna, Jakša Radek, Čapoun Otakar, Řezáč Jakub, Jirsová Kateřina, Franková Věra
Abstract excerpt
Hepatocyte nuclear factor 1 beta (HNF1B) is a tissue specific transcription factor, which seems to play an important role in the carcinogenesis of several tumors. In our study we focused on analyzing HNF1B in prostate carcinoma (PC) and adenomyomatous hyperplasia (AH), as well as its possible relation to the upstream gene EZH2 and downstream gene ECI2. The results of our study showed that on an...
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