Article
Heritability of haemodynamics in the ascending aorta.
Scientific reports - 1 Sept 2020
McGurk Kathryn A, Owen Benjamin, Watson William D, Nethononda Richard M, Cordell Heather J, Farrall Martin, Rider Oliver J, Watkins Hugh, Revell Alistair, Keavney Bernard D
Abstract excerpt
Blood flow in the vasculature can be characterised by dimensionless numbers commonly used to define the level of instabilities in the flow, for example the Reynolds number, Re. Haemodynamics play a key role in cardiovascular disease (CVD) progression. Genetic studies have identified mechanosensitive genes with causal roles in CVD. Given that CVD is highly heritable and abnormal blood flow may increase risk, we...
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