Article
IL-27 Regulated CD4+IL-10+ T Cells in Experimental Sjögren Syndrome.
Frontiers in immunology - 1 Jan 2020
Qi Jingjing, Zhang Zhuoya, Tang Xiaojun, Li Wenchao, Chen Weiwei, Yao Genhong
Abstract excerpt
Interleukin 27 (IL-27) plays diverse immune regulatory roles in autoimmune disorders and promotes the generation of IL-10-producing CD4+ T cells characterized by producing the immunosuppressive cytokine IL-10. However, whether IL-27 participates in pathological progress of Sjögren syndrome (SS) through regulating CD4+IL-10+ T cells remains unknown. Here we aimed to explore the potential role of IL-27 and...
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