Article
The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold.
RNA (New York, N.Y.) - 1 Dec 2020
Steckelberg Anna-Lena, Vicens Quentin, Costantino David A, Nix Jay C, Kieft Jeffrey S
Abstract excerpt
Exoribonuclease-resistant RNAs (xrRNAs) are discrete elements that block the progression of 5' to 3' exoribonucleases using specifically folded RNA structures. A recently discovered class of xrRNA is widespread in several genera of plant-infecting viruses, within both noncoding and protein-coding subgenomic RNAs. The structure of one such xrRNA from a dianthovirus revealed three-dimensional details of the...
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