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Article

Characterization of Uveal Melanoma Cell Lines and Primary Tumor Samples in 3D Culture

29 Jun 2020

Abstract excerpt

Purpose: Uveal melanoma (UM) typically spreads to the liver, where it is incurable, as there are limited therapeutic interventions available. This study aimed to standardize laboratory methods for generating three-dimensional (3D) spheroids using UM cell lines and primary UM (PUM) samples for use in drug screening. Methods: Six UM cell lines and nine PUM, of differing genetic characteristics were cultured in two...

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PMID: 32832244
DOI: 10.1167/tvst.9.7.39

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