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Adeno-Associated Virus Vector Mobilization, Risk Versus Reality

24 Aug 2020

Abstract excerpt

Recombinant adeno-associated viral (rAAV) vector mobilization is a largely theoretical process in which intact AAV vectors spread or “mobilize” from transduced cells and infect additional cells within, or external of, the initial host. This process can be helper virus-independent (vector alone) or helper virus-dependent ( de novo rAAV production facilitated by superinfection of both wild-type AAV [wtAAV] and...

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PMID: 32829671
DOI: 10.1089/hum.2020.118

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