Article
Polymorphisms Involved in Response to Biological Agents Used in Rheumatoid Arthritis.
Biomolecules - 19 Aug 2020
Pallio Giovanni, Mannino Federica, Irrera Natasha, Eid Ali H, Squadrito Francesco, Bitto Alessandra
Abstract excerpt
Rheumatoid arthritis (RA) is a systemic disease that leads to joint destruction. During the last decade, the therapy of RA has been principally based on biological drugs. Although the efficacy of biological therapy has been established, patients demonstrated a high heterogeneity in clinical response to treatment. Several genetic polymorphisms play a part in the different response to biological drugs. This review...
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