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Article

Preventative therapeutic approaches for hypertrophic cardiomyopathy.

The Journal of physiology - 1 Jul 2021

Solomon Tanya, Filipovska Aleksandra, Hool Livia, Viola Helena

Abstract excerpt

Sarcomeric gene mutations are associated with the development of hypertrophic cardiomyopathy (HCM). Current drug therapeutics for HCM patients are effective in relieving symptoms, but do not prevent or reverse disease progression. Moreover, due to heterogeneity in the clinical manifestations of the disease, patients experience variable outcomes in response to therapeutics. Mechanistically, alterations in calcium...

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Identifiers

PMID: 32822065
DOI: 10.1113/JP279410
PMCID: PMC8359240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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