Article
Mechanisms of disease: hypertrophic cardiomyopathy.
Nature reviews. Cardiology - 25 Oct 2011
Frey Norbert, Luedde Mark, Katus Hugo A
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is the most-common monogenically inherited form of heart disease, characterized by thickening of the left ventricular wall, contractile dysfunction, and potentially fatal arrhythmias. HCM is also the most-common cause of sudden cardiac death in individuals younger than 35 years of age. Much progress has been made in the elucidation of the genetic basis of HCM, resulting in the...
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