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Article

Complex genetic mechanisms in glaucoma: An overview

8 Dec 2010

Abstract excerpt

Glaucomas comprise a group of hereditary optic neuropathies characterized by progressive and irreversible visual field loss and damage to the optic nerve head. It is a complex disease with multiple molecular mechanisms underlying its pathogenesis. Genetic heterogeneity is the hallmark of all glaucomas and multiple chromosomal loci have been linked to the disease, but only a few genes have been characterized, viz....

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PMID: 21150032
DOI: 10.4103/0301-4738.73685

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