Article
A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population.
Translational vision science & technology - 1 May 2020
Miller Brendan, Torres Mina, Jiang Xuejuan, McKean-Cowdin Roberta, Nousome Darryl, Kim Su-Jeong, Mehta Hemal H, Yen Kelvin, Cohen Pinchas, Varma Rohit
Abstract excerpt
Purpose: Over 9.5 million Latinos could be affected by cataracts by 2050. However, no known cataract genetic risk alleles have been identified in Latinos. Moreover, no mitochondrial genome-wide association studies (MiWAS) have been conducted on cataracts in a Latino cohort despite the association between mitochondrial dysfunction and cataracts. Our purpose was to identify a mitochondrial DNA variant that...
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