Article
GSVA score reveals molecular signatures from transcriptomes for biomaterials comparison.
Journal of biomedical materials research. Part A - 1 Jun 2021
Ferreira Marcel R, Santos Gerson A, Biagi Carlos A, Silva Junior Wilson A, Zambuzzi Willian F
Abstract excerpt
Two in silico methodologies were implemented to reveal the molecular signatures of inorganic hydroxyapatite and β-TCP materials from a transcriptome database to compare biomaterials. To test this new methodology, we choose the array E-MTAB-7219, which contains the transcription profile of osteoblastic cell line seeded onto 15 different biomaterials up to 48 hr. The expansive potential of the methodology was...
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