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Mechanism of 2′-fucosyllactose degradation by human-associated Akkermansia

1 Feb 2024

Abstract excerpt

ABSTRACT Among the first microorganisms to colonize the human gut of breastfed infants are bacteria capable of fermenting human milk oligosaccharides (HMOs). One of the most abundant HMOs, 2′-fucosyllactose (2′-FL), may specifically drive bacterial colonization of the intestine. Recently, differential growth has been observed across multiple species of Akkermansia on various HMOs including 2′-FL. In culture, we...

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PMID: 38299857
DOI: 10.1128/jb.00334-23

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