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Article

The mitochondria regulation of stem cell aging.

Mechanisms of ageing and development - 1 Oct 2020

Wan Yong, Finkel Toren

Abstract excerpt

Mitochondrial dysfunction and stem cell exhaustion are among the nine separate hallmarks of aging. Emerging evidence however suggests that mitochondrial activity can have a profound influence on the self-renewal and function of stem cells, thus mechanistically linking mitochondrial function and stem cell decline. In this review, we discuss how accumulation of mtDNA mutations or alterations in mitochondrial...

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Identifiers

PMID: 32818514
DOI: 10.1016/j.mad.2020.111334
PMCID: PMC7541753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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