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Article

Urinary DNA Methylation Test for Bladder Cancer Diagnosis

30 Jan 2025

Abstract excerpt

Importance: An accurate noninvasive biomarker test is needed for the early diagnosis of bladder cancer. Objective: To evaluate the performance of a urinary DNA methylation test (PENK methylation) and compare its diagnostic accuracy with that of the nuclear matrix protein 22 (NMP22) test or urine cytology test. Design, Setting, and Participants: In this prospective multicenter study at 10 sites in the Republic of...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 39883469
DOI: 10.1001/jamaoncol.2024.6160

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