Article
Comparative Analysis of Urine Fractions for Optimal Bladder Cancer Detection Using DNA Methylation Markers
2 Apr 2020
Abstract excerpt
DNA methylation analysis of full void urine and urine pellet seems promising for bladder cancer (BC) detection and surveillance. Urinary cell-free DNA from urine supernatant is now gaining interest for other molecular tests in BC. This study aims to evaluate which urine fraction is preferred for BC diagnosis using methylation markers: full void urine, urine pellet or supernatant. Methylation levels of nine...
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