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Article

Phenome-wide examination of comorbidity burden and multiple sclerosis disease severity.

Neurology(R) neuroimmunology & neuroinflammation - 1 Nov 2020

Zhang Tingting, Goodman Matthew, Zhu Feng, Healy Brian, Carruthers Robert, Chitnis Tanuja, Weiner Howard, Cai Tianxi, De Jager Philip, Tremlett Helen, Xia Zongqi

Abstract excerpt

OBJECTIVE: We assessed the comorbidity burden associated with multiple sclerosis (MS) severity by performing a phenome-wide association study (PheWAS). METHODS: We conducted a PheWAS in 2 independent cohorts: a discovery (Boston, United States; 1993-2014) and extension cohort (British Columbia, Canada; 1991-2008). We included adults with MS, ≥1 Expanded Disability Status Scale (EDSS) score, and ≥1 International...

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Source

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Identifiers

PMID: 32817202
DOI: 10.1212/NXI.0000000000000864
PMCID: PMC7673286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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