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Article

Construction of a reference material panel for detecting KRAS/NRAS/EGFR/BRAF/MET mutations in plasma ctDNA.

Journal of clinical pathology - 1 May 2021

Xu Jun, Qu Shoufang, Sun Nan, Zhang Wenxin, Zhang Juanli, Song Qingtao, Lin Mufei, Gao Wei, Zheng Qiaosong, Han Mipeng, Na Chenglong, Xu Ren, Chang Xiaoyan, Yang Xuexi, Huang Jie

Abstract excerpt

BACKGROUND: The absence of high-quality next-generation sequencing (NGS) reference material (RM) has impeded the clinical use of liquid biopsies with plasma cell-free DNA (cfDNA) in China. OBJECTIVE: This study aimed to develop a national RM panel for external quality assessment and performance evaluation during kit registration of non-small-cell lung cancer (NSCLC)-related Kirsten rat sarcoma viral oncogene...

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Identifiers

PMID: 32817175
DOI: 10.1136/jclinpath-2020-206745
PMCID: PMC8070650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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